Structure of PDB 7rh2 Chain B Binding Site BS02

Receptor Information
>7rh2 Chain B (length=109) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NGKLRQWLIDQIDSGKYPGLVWENEEKSIFRIPWKHAGRQDYNREEDAAL
FKAWALFKGKFREGIDKPDPPTWKTRLRCALNKSNDFEELVERSQLDISD
PYKVYRIVP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7rh2 The molecular basis for the development of adult T-cell leukemia/lymphoma in patients with an IRF4 K59R mutation.
Resolution2.47 Å
Binding residue
(original residue number in PDB)		G22 K23 L24 W74 K78 K80 R96 C99 K103
Binding residue
(residue number reindexed from 1)		G2 K3 L4 W54 K58 K60 R76 C79 K83
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:7rh2, PDBe:7rh2, PDBj:7rh2
PDBsum7rh2
PubMed34913532
UniProtQ15306|IRF4_HUMAN Interferon regulatory factor 4 (Gene Name=IRF4)

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