Structure of PDB 7r86 Chain B Binding Site BS02

Receptor Information
>7r86 Chain B (length=285) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ASCPGACVCYNEPKVTTSCPQQGLQAVPTGIPASSQRIFLHGNRISHVPA
ASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHVVDPT
TFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNLQALPDNTF
RDLGNLTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVARVHPHAFRD
LGRLMTLYLFANNLSMLPAEVLMPLRSLQYLRLNDNPWVCDCRARPLWAW
LQKFRGSSSEVPCNLPQRLADRDLKRLAASDLEGC
Ligand information
Ligand IDPAB
InChIInChI=1S/C7H7NO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4H,8H2,(H,9,10)
InChIKeyALYNCZNDIQEVRV-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341Nc1ccc(cc1)C(O)=O
ACDLabs 10.04O=C(O)c1ccc(N)cc1
OpenEye OEToolkits 1.5.0c1cc(ccc1C(=O)O)N
FormulaC7 H7 N O2
Name4-AMINOBENZOIC ACID
ChEMBLCHEMBL542
DrugBankDB02362
ZINCZINC000000000920
PDB chain7r86 Chain A Residue 403 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7r86 RTN4/NoGo-receptor binding to BAI adhesion-GPCRs regulates neuronal development.
Resolution1.65 Å
Binding residue
(original residue number in PDB)		H65 W87
Binding residue
(residue number reindexed from 1)		H41 W63
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:7r86, PDBe:7r86, PDBj:7r86
PDBsum7r86
PubMed34758294
UniProtQ99PI8|RTN4R_MOUSE Reticulon-4 receptor (Gene Name=Rtn4r)

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