Structure of PDB 7qpc Chain B Binding Site BS02

Receptor Information
>7qpc Chain B (length=327) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MGISWLDIYHVVSATVPLYVSMTLGFLSARHLKLFSPEQCAGINKFVAKF
SIPLLSFQIISENNPFKMSPKLILSDILQKFLVVVVLAMVLRFWHPTGGR
GGKLGWVITGLSISVLPNTLILGMPILSAIYGDEAASILEQIVVLQSLIW
YTILLFLFELNAARAGTMKILLKAWRKLIINPNTYATLIGIIWATLHFRL
GWNLPEMIDKSIHLLSDGGLGMAMFSLGLFMASQSSIIACGTKMAIITML
LKFVLGPALMIASAYCIRLKSTLFKVAILQAALPQGVVPFVFAKEYNLHP
EIISTGVIFGMLIALPTTLAYYFLLDL
Ligand information
Ligand IDDLP
InChIInChI=1S/C44H80NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h14-17,20-23,42H,6-13,18-19,24-41H2,1-5H3/b16-14-,17-15-,22-20-,23-21-/t42-/m1/s1
InChIKeyFVXDQWZBHIXIEJ-LNDKUQBDSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0CCCCC\C=C/C\C=C/CCCCCCCC(=O)OC[C@H](CO[P@@](=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCC\C=C/C\C=C/CCCCC
CACTVS 3.341CCCCCC=CCC=CCCCCCCCC(=O)OC[CH](CO[P]([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCC=CCCCCC
ACDLabs 10.04O=C(OCC(OC(=O)CCCCCCC\C=C/C\C=C/CCCCC)COP([O-])(=O)OCC[N+](C)(C)C)CCCCCCC\C=C/C\C=C/CCCCC
OpenEye OEToolkits 1.5.0CCCCCC=CCC=CCCCCCCCC(=O)OCC(COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCC=CCCCCC
CACTVS 3.341CCCCC/C=C\C\C=C/CCCCCCCC(=O)OC[C@H](CO[P]([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCC\C=C/C/C=C\CCCCC
FormulaC44 H80 N O8 P
Name1,2-DILINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE;
DI-LINOLEOYL-3-SN-PHOSPHATIDYLCHOLINE
ChEMBL
DrugBankDB04372
ZINC
PDB chain7qpc Chain B Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7qpc Structures and mechanism of the plant PIN-FORMED auxin transporter.
Resolution3.44 Å
Binding residue
(original residue number in PDB)		K44 K48 F49 P222 I229
Binding residue
(residue number reindexed from 1)		K45 K49 F50 P182 I189
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0010329 auxin efflux transmembrane transporter activity
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0009555 pollen development
GO:0009734 auxin-activated signaling pathway
GO:0010315 auxin export across the plasma membrane
GO:0055085 transmembrane transport
GO:0060918 auxin transport
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0071944 cell periphery

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7qpc, PDBe:7qpc, PDBj:7qpc
PDBsum7qpc
PubMed35768502
UniProtQ9LFP6|PIN8_ARATH Auxin efflux carrier component 8 (Gene Name=PIN8)

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