Structure of PDB 7pnw Chain B Binding Site BS02

Receptor Information

>7pnw Chain B (length=223) Species: 10090 (Mus musculus)

GDDFQSRILDTPLQHSDFFNVKELFSVKSLFEARVHLGHKAGCRHRFMEP
YIFGNRLGQDIIDLDQTALNLQLALNFTAHVAYRKGIILFVSRNRQFSHL
IETTAQACGEYAHTRYFKGGLLTNAQLLFGPSVRLPDLIIFLHTLNNVFE
PHVAVRDAAKMNIPTVGIVDTNCNPCLITYPIPGNDDSPQAIQLFCKLFR
TTINRAKEKRRQMEALHRLQSPK

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 7pnw Chain B Residue 301

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7pnw Mechanism of mitoribosomal small subunit biogenesis and preinitiation.
• Resolution: 3.09 Å
• Binding residue (original residue number in PDB): H90 D221 D237 D238
• Binding residue (residue number reindexed from 1): H39 D170 D186 D187
• Annotation score: 4

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0006412 translation
• GO:0032543 mitochondrial translation
• GO:0061668 mitochondrial ribosome assembly

Cellular Component

• GO:0005739 mitochondrion
• GO:0005743 mitochondrial inner membrane
• GO:0005763 mitochondrial small ribosomal subunit
• GO:0005840 ribosome
• GO:0015935 small ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:7pnw, PDBe:7pnw, PDBj:7pnw
• PDBsum: 7pnw
• PubMed: 35676484
• UniProt: Q924T2|RT02_MOUSE Small ribosomal subunit protein uS2m (Gene Name=Mrps2)