Structure of PDB 7pdf Chain B Binding Site BS02

Receptor Information

>7pdf Chain B (length=341) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

KQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVKATKVQDIKNNL
KEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEH
AKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQDDYVPSDQDLLR
CRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVA
SSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAE
KVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRIS
TASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQ

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

7pdf Chain B Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7pdf Structural basis of adenylyl cyclase 9 activation.
Resolution	3.8 Å
Binding residue (original residue number in PDB)	S54 T204
Binding residue (residue number reindexed from 1)	S27 T155
Annotation score	1

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003924	GTPase activity
GO:0005525	GTP binding
GO:0019001	guanyl nucleotide binding
GO:0031683	G-protein beta/gamma-subunit complex binding

	Biological Process
GO:0007165	signal transduction
GO:0007186	G protein-coupled receptor signaling pathway

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Molecular Function

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Biological Process

External links

PDB	RCSB:7pdf, PDBe:7pdf, PDBj:7pdf
PDBsum	7pdf
PubMed	35210418
UniProt	P04896\|GNAS2_BOVIN Guanine nucleotide-binding protein G(s) subunit alpha isoforms short (Gene Name=GNAS)

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