Structure of PDB 7p0h Chain B Binding Site BS02

Receptor Information
>7p0h Chain B (length=411) Species: 32630 (synthetic construct) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EKVEMYIKNLQDDSLTVRINAANALGKIGDERAVEPLIKALKDEDALVRL
SAAWALGKIGDERAVEPLIKALKDEDSDVRYRAATALGQIGDERAVEPLI
KALKDEDERVRQSAAGALGQIGDERAVEPLIKALKDEDWRVRQEAAFALG
QIGDERAVEPLIKALKDEDSAVRWAAALALGKIGGERVRAAMEKLAETGT
GFARKVAVNYLETHGGSAGSPMRCLTCLKLSFKPLCPNCLNDLPLSLKVR
VLEGVSVYSFYAYSEIEELIKSKYALIGSRILPLLSQKAGAEFVKILQEQ
GLNIPLYGIAIDDKIKSFYSHSAALLKGFCQGNLKPTYGRLRANNAVSYA
GKSLEFRANNPRNFTFKGDESLDYFLLDDIITTGTTLKEALKYLKTLNIK
VHFAIALCSAD
Ligand information
Ligand IDPRP
InChIInChI=1S/C5H13O14P3/c6-3-2(1-16-20(8,9)10)17-5(4(3)7)18-22(14,15)19-21(11,12)13/h2-7H,1H2,(H,14,15)(H2,8,9,10)(H2,11,12,13)/t2-,3-,4-,5-/m1/s1
InChIKeyPQGCEDQWHSBAJP-TXICZTDVSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C1C(C(C(O1)OP(=O)(O)OP(=O)(O)O)O)O)OP(=O)(O)O
OpenEye OEToolkits 1.5.0C([C@@H]1[C@H]([C@H]([C@H](O1)O[P@@](=O)(O)OP(=O)(O)O)O)O)OP(=O)(O)O
CACTVS 3.341O[CH]1[CH](O)[CH](O[CH]1CO[P](O)(O)=O)O[P](O)(=O)O[P](O)(O)=O
ACDLabs 10.04O=P(OC1OC(C(O)C1O)COP(=O)(O)O)(O)OP(=O)(O)O
CACTVS 3.341O[C@H]1[C@@H](O)[C@H](O[C@@H]1CO[P](O)(O)=O)O[P@](O)(=O)O[P](O)(O)=O
FormulaC5 H13 O14 P3
Name1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose;
ALPHA-PHOSPHORIBOSYLPYROPHOSPHORIC ACID;
1-O-pyrophosphono-5-O-phosphono-alpha-D-ribose;
1-O-pyrophosphono-5-O-phosphono-D-ribose;
1-O-pyrophosphono-5-O-phosphono-ribose
ChEMBL
DrugBankDB01632
ZINCZINC000008215630
PDB chain7p0h Chain B Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7p0h ComFC mediates transport and handling of single-stranded DNA during natural transformation.
Resolution2.499 Å
Binding residue
(original residue number in PDB)		Y289 S363 Y364 R372 R377 D393 D394 I395 T397 T398 G399 T401
Binding residue
(residue number reindexed from 1)		Y274 S348 Y349 R357 R362 D378 D379 I380 T382 T383 G384 T386
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:7p0h, PDBe:7p0h, PDBj:7p0h
PDBsum7p0h
PubMed35414142
UniProtO26008

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