Structure of PDB 7ndj Chain B Binding Site BS02

Receptor Information
>7ndj Chain B (length=192) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GENLRPVVINGSNVAMSHGNKEVFSCRGIKLAVDWFLERGHKDITVFVPA
WRKEQSRPDALITDQEILRKLEKEKILVFTPSRRVQGRRVVCYDDRFIVK
LAFESDGIIVSNDNYRDLANEKPEWKKFIDERLLMYSFVNDKFMPPDDPL
GRHGPSLDNFLRKKPIVPEHKKQPCPYGKKCTYGHKCKYYHP
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7ndj Chain B Residue 406 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7ndj PIN and CCCH Zn-finger domains coordinate RNA targeting in ZC3H12 family endoribonucleases.
Resolution1.649 Å
Binding residue
(original residue number in PDB)
C306 C312 C318 H322
Binding residue
(residue number reindexed from 1)
C175 C181 C187 H191
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.-.-
External links
PDB RCSB:7ndj, PDBe:7ndj, PDBj:7ndj
PDBsum7ndj
PubMed33950203
UniProtQ5DTV4|ZC12C_MOUSE Probable ribonuclease ZC3H12C (Gene Name=Zc3h12c)

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