Structure of PDB 7n3y Chain B Binding Site BS02

Receptor Information
>7n3y Chain B (length=371) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GKSENTIRFLTFNVNGIRTFFHYQPFSQMNQSLRSVFDFFRADIITFQQL
KTEKLSISKWGRVDGFYSFISIPQTRKGYSGVGCWIRIPEKNHPLYHALQ
VVKAEEGITGYLTIKNGKHSAISYRNDVNQGIGGYDSLDPDLDEKSALEL
DSEGRCVMVELACGIVIISVYCPANSNSSEEGEMFRLRFLKVLLRRVRNL
DKIGKKIVLMGNVNVCRDLIDSADTLEQFSIPITDPMGGTKLEAQYRDKA
IQFIINPDTPHRRIFNQILADSLLPDASKRGILIDTTRLIQTRNRLKMYT
VWNMLKNLRPSNYGSRIDFILVSLKLERCIKAADILPDILGSDHCPVYSD
LDILDQVPIPKFEARYKYNLR
Ligand information
Receptor-Ligand Complex Structure
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PDB7n3y Molecular basis for processing of topoisomerase 1-triggered DNA damage by Apn2/APE2.
Resolution2.73 Å
Binding residue
(original residue number in PDB)		R257 D258 I261 Q262 P285 D286
Binding residue
(residue number reindexed from 1)		R247 D248 I251 Q252 P275 D276
Enzymatic activity
Enzyme Commision number 3.1.11.2: exodeoxyribonuclease III.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003824 catalytic activity
GO:0004518 nuclease activity
GO:0004519 endonuclease activity
Biological Process
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:7n3y, PDBe:7n3y, PDBj:7n3y
PDBsum7n3y
PubMed36198268
UniProtP38207|APN2_YEAST DNA-(apurinic or apyrimidinic site) endonuclease 2 (Gene Name=APN2)

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