Structure of PDB 7mk1 Chain B Binding Site BS02

Receptor Information
>7mk1 Chain B (length=121) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KENKKLLCRKCKALACYTADVRVIEECHYTVLGDAFKECFVSRPHPKPKQ
FSSFEKRAKIFCARQNCSHDWGIHVKYKTFEIPVIKIESFVVEDIATGVQ
TLYSKWKDFHFEKIPFDPAEM
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7mk1 Chain B Residue 1001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7mk1 Evolving A RIG-I Antagonist: A Modified DNA Aptamer Mimics Viral RNA.
Resolution1.9 Å
Binding residue
(original residue number in PDB)		C810 C813 C864 C869
Binding residue
(residue number reindexed from 1)		C8 C11 C62 C67
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
External links
PDB RCSB:7mk1, PDBe:7mk1, PDBj:7mk1
PDBsum7mk1
PubMed34487794
UniProtO95786|RIGI_HUMAN Antiviral innate immune response receptor RIG-I (Gene Name=RIGI)

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