Structure of PDB 7lxr Chain B Binding Site BS02

Receptor Information
>7lxr Chain B (length=344) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QNIQVYVRVRPLNSRERCIRSAEVVDVVGPREVVTRHTLDSKLTKKFTFD
RSFGPESKQCDVYSVVVSPLIEEVLNGYNCTVFAYGQTGTGKTHTMVGNE
TAELKSSWEDDSDIGIIPRALSHLFDELRMMEVEYTMRISYLELYNEELC
DLLSTDDTTKIRIFDDSTKKGSVIIQGLEEIPVHSKDDVYKLLEKGKERR
KTATTLMNAQSSRSHTVFSIVVHIRENGIEGEDMLKIGKLNLVDLAGSEN
VKGIRVRETVNINQSLLTLGRVITALVDRAPHVPYRESKLTRLLQESLGG
RTKTSIIATISPGHKDIEETLSTLEYAHRAKNIQNKPEVNQKLT
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain7lxr Chain B Residue 404 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7lxr ATP hydrolysis in Eg5 kinesin involves a catalytic two-water mechanism
Resolution1.744 Å
Binding residue
(original residue number in PDB)		T110 S229
Binding residue
(residue number reindexed from 1)		T93 S212
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0007018 microtubule-based movement

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Molecular Function
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Biological Process
External links
PDB RCSB:7lxr, PDBe:7lxr, PDBj:7lxr
PDBsum7lxr
PubMed
UniProtP46863|KL61_DROME Kinesin-like protein Klp61F (Gene Name=Klp61F)

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