Structure of PDB 7lle Chain B Binding Site BS02

Receptor Information
>7lle Chain B (length=445) Species: 1877 (Micromonospora echinospora) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNYRELIERARRTTAAEEYDISGRYPSVIAHAEGAWMTDLSGNRYVDLTG
ADAAVILGYRHPAVNEAITRQIRDYGTTFASTLSVPRVELAERMCERYEC
AEKVVFHKTGTEGTAMAVRLARAATGRELVLSSGYHGWHEWQMAGEEFGY
QQSTGVVGFGYNEKALAKMLEAFGEQVAGVIVSPEVLYFDLDHYRRMSAL
CARYDVPFMLDEVYTGFRAGPKGVHGLGVPADVVVLGKGLANGHSLAAVM
GRRDIIDAYDVSGIQGTYTREVPPMAAALAVFEVLDTPGVYEHAEAMGRR
LADGMREILTGEGIPNWVGGPALMFDVVLPNDDLGWEIYKTAHDFGVYFE
DSGTQLVTAAFDEAAVDHALTAFRKATRQVVADRPDIAPTSGGELTEERK
LDFAEEAFGGLLRDDERTNALIDETIEKVVNRDRSIKPVLFPAQN
Ligand information
Ligand IDPLP
InChIInChI=1S/C8H10NO6P/c1-5-8(11)7(3-10)6(2-9-5)4-15-16(12,13)14/h2-3,11H,4H2,1H3,(H2,12,13,14)
InChIKeyNGVDGCNFYWLIFO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341Cc1ncc(CO[P](O)(O)=O)c(C=O)c1O
OpenEye OEToolkits 1.5.0Cc1c(c(c(cn1)COP(=O)(O)O)C=O)O
ACDLabs 10.04O=P(O)(O)OCc1cnc(c(O)c1C=O)C
FormulaC8 H10 N O6 P
NamePYRIDOXAL-5'-PHOSPHATE;
VITAMIN B6 Phosphate
ChEMBLCHEMBL82202
DrugBankDB00114
ZINCZINC000001532514
PDB chain7lle Chain B Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7lle Crystal structure of GenB4 in complex with external aldimine of PLP-sisomicin
Resolution1.704 Å
Binding residue
(original residue number in PDB)		G110 T111 Y135 H136 S183 D211 V213 Y214 K238
Binding residue
(residue number reindexed from 1)		G110 T111 Y135 H136 S183 D211 V213 Y214 K238
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008483 transaminase activity
GO:0030170 pyridoxal phosphate binding

View graph for
Molecular Function
External links
PDB RCSB:7lle, PDBe:7lle, PDBj:7lle
PDBsum7lle
PubMed
UniProtQ6QVT7

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