Structure of PDB 7ljl Chain B Binding Site BS02

Receptor Information
>7ljl Chain B (length=348) Species: 550 (Enterobacter cloacae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SMELQPQFNEFLANIRPTDTQKEDWKSGARTLRERLKNFEPLKEIVVSTF
LQGSIRRSTAIRPLGDKRPDVDIVVVTNLDHTRMSPTDAMDLFIPFLEKY
YPGKWETQGRSFGITLSYVELDLVITAIPESGAEKSHLEQLYKSESVLTV
NSLEEQTDWRLNKSWTPNVEDAPASEWKAHPLVLPDREKNEWGRTHPLAQ
IRWTAEKNRLCNGHYINLVRAVKWWRQQNSEDLPKYPKGYPLEHLIGNAL
DNGTTSMAQGLVQLMDTFLSRWAAIYNQKSKPWLSDHGVAEHDVMARLTA
EDFCSFYEGIASAAEIARNALASEEPQESAQLWRQLFGSKFPLPGNGG
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain7ljl Chain B Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7ljl Molecular basis of CD-NTase nucleotide selection in CBASS anti-phage defense.
Resolution1.45 Å
Binding residue
(original residue number in PDB)		D69 D71
Binding residue
(residue number reindexed from 1)		D70 D72
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.7.-
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0005525 GTP binding
GO:0016779 nucleotidyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0009117 nucleotide metabolic process
GO:0051607 defense response to virus

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7ljl, PDBe:7ljl, PDBj:7ljl
PDBsum7ljl
PubMed34077735
UniProtP0DSP4|CDND2_ENTH5 Cyclic AMP-AMP-GMP synthase (Gene Name=cdnD02)

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