Structure of PDB 7kdc Chain B Binding Site BS02

Receptor Information
>7kdc Chain B (length=180) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VRSVKVVLVGDGGCGKTSLLMVFADGAFPESYTPTVFERYMVNLQVKGKP
VHLHIWDTAGLDDYDRLRPLFYPDASVLLLCFDVTSPNSFDNIFNRWYPE
VNHFCKKVPIIVVGCKTDLRKDKSLVNKLRRNGLEPVTYHRGQEMARSVG
AVAYLECSARLHDNVHAVFQEAAEVALSSR
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain7kdc Chain B Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7kdc A putative structural mechanism underlying the antithetic effect of homologous RND1 and RhoD GTPases in mammalian plexin regulation.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		T31 T49
Binding residue
(residue number reindexed from 1)		T17 T35
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0007264 small GTPase-mediated signal transduction

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Molecular Function
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Biological Process
External links
PDB RCSB:7kdc, PDBe:7kdc, PDBj:7kdc
PDBsum7kdc
PubMed34114565
UniProtO00212|RHOD_HUMAN Rho-related GTP-binding protein RhoD (Gene Name=RHOD)

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