Structure of PDB 7kd8 Chain B Binding Site BS02

Receptor Information

>7kd8 Chain B (length=208) Species: 1196325 (Pseudomonas putida DOT-T1E) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

RRTKEEAQETRAQIIEAAERAFYKRGVARTTLADIAELAGVTRGAIYWHF
NNKAELVQALLDSLHETHDHLARASESEDEVDPLGCMRKLLLQVFNELVL
DARTRRINEILHHKCEFTDDMCEIRQQRQSAVLDIHKGWTLALANAVRRG
QLPGELDAERAAVALYAYVDGLIRRWLLLPDSVDLLGDVEKWVDTGLDML
RLSPALRK

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

7kd8 Chain B Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	7kd8 Epistasis shapes the fitness landscape of an allosteric specificity switch.
Resolution	1.71 Å
Binding residue (original residue number in PDB)	T69 E99
Binding residue (residue number reindexed from 1)	T67 E97
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0000976	transcription cis-regulatory region binding
GO:0001217	DNA-binding transcription repressor activity
GO:0003677	DNA binding
GO:0003700	DNA-binding transcription factor activity

	Biological Process
GO:0006355	regulation of DNA-templated transcription
GO:0045892	negative regulation of DNA-templated transcription

	Cellular Component
GO:0032993	protein-DNA complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:7kd8, PDBe:7kd8, PDBj:7kd8
PDBsum	7kd8
PubMed	34548494
UniProt	Q9AIU0\|TTGR_PSEPT HTH-type transcriptional regulator TtgR (Gene Name=ttgR)

[Back to BioLiP]