Structure of PDB 7kbu Chain B Binding Site BS02

Receptor Information
>7kbu Chain B (length=192) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
CKRGHICVCQDPVTCPPTKPLDQVCGTDNQTYASSCHLFATKCRLEGTKK
GHQLQLDYFGACKSIPTCTDFEVIQFPLRMRDWLKNILMQLYEANGDHPI
DLLLRDFKKNYHMYVYPVHWQFSELDQHPMDRVLTHSELAPLRASLVPME
HCITRFFEECDPNKDKHITLKEWGHCFGIKEEDIDENLLFAS
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain7kbu Chain B Residue 702 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7kbu Interplay between hevin, SPARC, and MDGAs: Modulators of neurexin-neuroligin transsynaptic bridges.
Resolution2.27 Å
Binding residue
(original residue number in PDB)		D635 N637 D639 H641 E646
Binding residue
(residue number reindexed from 1)		D161 N163 D165 H167 E172
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Cellular Component
GO:0005615 extracellular space

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Molecular Function
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Cellular Component
External links
PDB RCSB:7kbu, PDBe:7kbu, PDBj:7kbu
PDBsum7kbu
PubMed33535026
UniProtQ14515|SPRL1_HUMAN SPARC-like protein 1 (Gene Name=SPARCL1)

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