Structure of PDB 7k78 Chain B Binding Site BS02

Receptor Information
>7k78 Chain B (length=79) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DNIQGITKPAIRRLARRGGVKRISGLIYEEVRAVLKSFLESVIRDSVTYT
EHAKRKTVTSLDVVYALKRQGRTLYGFGG
Ligand information
>7k78 Chain J (length=116) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
tatttcttttttaactttcggaaatcaaatacactaatattttaaatttt
attttttaaaaataaactactttttattttttactttttttaaaaatata
ataaaatcaaatatca
Receptor-Ligand Complex Structure
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PDB7k78 Structural and dynamic mechanisms of CBF3-guided centromeric nucleosome formation.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		R36 R46 I47 G49 R79 K80 T81
Binding residue
(residue number reindexed from 1)		R12 R22 I23 G25 R55 K56 T57
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0042802 identical protein binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006325 chromatin organization
GO:0006334 nucleosome assembly
GO:0006355 regulation of DNA-templated transcription
GO:0042790 nucleolar large rRNA transcription by RNA polymerase I
GO:0045943 positive regulation of transcription by RNA polymerase I
Cellular Component
GO:0000500 RNA polymerase I upstream activating factor complex
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome
GO:0031298 replication fork protection complex
GO:0032991 protein-containing complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7k78, PDBe:7k78, PDBj:7k78
PDBsum7k78
PubMed33741944
UniProtP02309|H4_YEAST Histone H4 (Gene Name=HHF1)

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