Structure of PDB 7fng Chain B Binding Site BS02

Receptor Information
>7fng Chain B (length=300) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNTVPFTSAPIEVTIGIDQYSFNVKENQPFHGIKDIPIGHVHVIHFQHAD
NSSMRYGYWFDCRMGNFYIQYDPKDGLYKMMEERDGAKFENIVHNFKERQ
MMVSYPKIDEDDTWYNLTEFVQMDKIRKIVRKDENQFSYVDSSMTTVQEN
ELSDPAHSLNYTVINFKSREAIRPGHEMEDFLDKSYYLNTVMLQGIFKNS
SNYFGELQFAFLNAMFFGNYGSSLQWHAMIELICSSATVPKHMLDKLDEI
LYYQIKTLPEQYSDILLNERVWNICLYSSFQKNSLHNTEKIMENKYPELL
Ligand information
Ligand IDLAZ
InChIInChI=1S/C9H10ClNO2/c10-8-3-1-7(2-4-8)9(13)11-5-6-12/h1-4,12H,5-6H2,(H,11,13)
InChIKeyGBARCMIFTACERW-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0c1cc(ccc1C(=O)NCCO)Cl
ACDLabs 10.04O=C(c1ccc(Cl)cc1)NCCO
CACTVS 3.341OCCNC(=O)c1ccc(Cl)cc1
FormulaC9 H10 Cl N O2
NameN-(2-AMINOETHYL)-P-CHLOROBENZAMIDE;
4-CHLORO-N-(2-HYDROXYETHYL)BENZAMIDE
ChEMBLCHEMBL1233960
DrugBankDB08082
ZINCZINC000001665476
PDB chain7fng Chain B Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7fng Large-Scale Crystallographic Fragment Screening Expedites Compound Optimization and Identifies Putative Protein-Protein Interaction Sites.
Resolution1.6 Å
Binding residue
(original residue number in PDB)		F22 V103 S104
Binding residue
(residue number reindexed from 1)		F22 V103 S104
Annotation score1
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:7fng, PDBe:7fng, PDBj:7fng
PDBsum7fng
PubMed36260741
UniProtP32357|AAR2_YEAST A1 cistron-splicing factor AAR2 (Gene Name=AAR2)

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