Structure of PDB 7fh4 Chain B Binding Site BS02

Receptor Information
>7fh4 Chain B (length=140) Species: 10506 (Paramecium bursaria Chlorella virus 1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KAEKFYSLACYHAQLFSKDPNTKVAALVIDNNNNIASVGYNGLPRGFEET
SDRWEKPMKYNYVVHAQANAIATAARNGVRLDGCSIITTLFPCKECSKLI
IQSGIRKVITSKPCKDSSWLESFSFSNEMFDECGIEVEYL
Ligand information
Ligand IDDCP
InChIInChI=1S/C9H16N3O13P3/c10-7-1-2-12(9(14)11-7)8-3-5(13)6(23-8)4-22-27(18,19)25-28(20,21)24-26(15,16)17/h1-2,5-6,8,13H,3-4H2,(H,18,19)(H,20,21)(H2,10,11,14)(H2,15,16,17)/t5-,6+,8+/m0/s1
InChIKeyRGWHQCVHVJXOKC-SHYZEUOFSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04O=P(O)(O)OP(=O)(O)OP(=O)(O)OCC2OC(N1C(=O)N=C(N)C=C1)CC2O
OpenEye OEToolkits 1.5.0C1C(C(OC1N2C=CC(=NC2=O)N)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O
CACTVS 3.341NC1=NC(=O)N(C=C1)[C@H]2C[C@H](O)[C@@H](CO[P@](O)(=O)O[P@](O)(=O)O[P](O)(O)=O)O2
OpenEye OEToolkits 1.5.0C1[C@@H]([C@H](O[C@H]1N2C=CC(=NC2=O)N)CO[P@@](=O)(O)O[P@@](=O)(O)OP(=O)(O)O)O
CACTVS 3.341NC1=NC(=O)N(C=C1)[CH]2C[CH](O)[CH](CO[P](O)(=O)O[P](O)(=O)O[P](O)(O)=O)O2
FormulaC9 H16 N3 O13 P3
Name2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE
ChEMBLCHEMBL560403
DrugBankDB03258
ZINCZINC000008215945
PDB chain7fh4 Chain B Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7fh4 Structural basis of a multi-functional deaminase in chlorovirus PBCV-1.
Resolution1.996 Å
Binding residue
(original residue number in PDB)		K20 Y42 G44 L45 R47 E51 N71
Binding residue
(residue number reindexed from 1)		K18 Y40 G42 L43 R45 E49 N69
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003824 catalytic activity
GO:0004132 dCMP deaminase activity
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006220 pyrimidine nucleotide metabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7fh4, PDBe:7fh4, PDBj:7fh4
PDBsum7fh4
PubMed35764100
UniProtO41078

[Back to BioLiP]