Structure of PDB 7d9x Chain B Binding Site BS02

Receptor Information
>7d9x Chain B (length=194) Species: 46680 (Pseudomonas nitroreducens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TTHFSIVDKDGNAVSNTYTLNWDFGSGVVVKGAGFLLNDEMDDFSSKPGV
ANAFGVVGSDANAIEPGKRMLSSMSPSIVTRDGHVSLVLGTPGGSRIFTS
IFQVLNNVYDFHLPLEKAVAAQRVHHQLLPKDTIYYDAYAPLTGKVADEL
KAMGYTLEDQGDNMGDIQAIRVNGKALETASDPRGRGVGMVVKP
Ligand information
Ligand IDGLY
InChIInChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
InChIKeyDHMQDGOQFOQNFH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C(=O)O)N
CACTVS 3.341NCC(O)=O
ACDLabs 10.04O=C(O)CN
FormulaC2 H5 N O2
NameGLYCINE
ChEMBLCHEMBL773
DrugBankDB00145
ZINCZINC000004658552
PDB chain7d9x Chain B Residue 602 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7d9x Mutagenesis and structure-based analysis of the role of Tryptophan525 of gamma-glutamyltranspeptidase from Pseudomonas nitroreducens.
Resolution1.74 Å
Binding residue
(original residue number in PDB)		D406 S435 S436
Binding residue
(residue number reindexed from 1)		D43 S72 S73
Annotation score1
Enzymatic activity
Enzyme Commision number 2.3.2.2: gamma-glutamyltransferase.
3.4.19.13: glutathione gamma-glutamate hydrolase.
Gene Ontology
Molecular Function
GO:0036374 glutathione hydrolase activity
Biological Process
GO:0006751 glutathione catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:7d9x, PDBe:7d9x, PDBj:7d9x
PDBsum7d9x
PubMed33288198
UniProtA0A6G6IRK3

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