Structure of PDB 7d8t Chain B Binding Site BS02
Receptor Information
>7d8t Chain B (length=199) Species:
9606,224324
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SLAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTIL
KASVDYIRKLQREQQRAKELENRQKKLEHACRHLLLRIQELGIEDFLKVD
LRVAKVLSAERVEGSEKLLKLTLSLGDEERTVVAGIAKYYTPEELVGKKI
VIVANLKPRKIFGIESQGMILAASDGENLSVIVPDRDVKEGAKLSAALE
Ligand information
>7d8t Chain D (length=16) [
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tgtaacatgtgtcccc
Receptor-Ligand Complex Structure
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PDB
7d8t
A unique hyperdynamic dimer interface permits small molecule perturbation of the melanoma oncoprotein MITF for melanoma therapy.
Resolution
3.201 Å
Binding residue
(original residue number in PDB)
E320 R323
Binding residue
(residue number reindexed from 1)
E16 R19
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0000049
tRNA binding
GO:0000166
nucleotide binding
GO:0004825
methionine-tRNA ligase activity
GO:0005524
ATP binding
GO:0046983
protein dimerization activity
Biological Process
GO:0006431
methionyl-tRNA aminoacylation
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Molecular Function
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Biological Process
External links
PDB
RCSB:7d8t
,
PDBe:7d8t
,
PDBj:7d8t
PDBsum
7d8t
PubMed
36588115
UniProt
O66738
;
O75030
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