Structure of PDB 7bai Chain B Binding Site BS02
Receptor Information
>7bai Chain B (length=121) Species:
9606
(Homo sapiens) [
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DKENKKLLCRKCKALACYTADVRVIEECHYTVLGDAFKECFVSRPHPKPK
QFSSFEKRAKIFCARQNCSHDWGIHVKYKTFEIPVIKIESFVVEDIATGV
QTLYSKWKDFHFEKIPFDPAE
Ligand information
>7bai Chain D (length=12) [
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gacgcuagcguc
............
Receptor-Ligand Complex Structure
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PDB
7bai
A conserved isoleucine in the RNA sensor RIG-I controls immune tolerance to mitochondrial RNA
Resolution
3.4 Å
Binding residue
(original residue number in PDB)
C829 H830 K851 F853 K858 K861 G874 K888 K907
Binding residue
(residue number reindexed from 1)
C28 H29 K50 F52 K57 K60 G73 K87 K106
Enzymatic activity
Enzyme Commision number
3.6.4.13
: RNA helicase.
External links
PDB
RCSB:7bai
,
PDBe:7bai
,
PDBj:7bai
PDBsum
7bai
PubMed
UniProt
O95786
|RIGI_HUMAN Antiviral innate immune response receptor RIG-I (Gene Name=RIGI)
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