Structure of PDB 7bah Chain B Binding Site BS02
Receptor Information
>7bah Chain B (length=122) Species:
9606
(Homo sapiens) [
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DKENKKLLCRKCKALACYTADVRVIEECHYTVLGDAFKECFVSRPHPKPK
QFSSFEKRAKIFCARQNCSHDWGIHVKYKTFEIPVIKIESFVVEDIATGV
QTLYSKWKDFHFEKIPFDPAEM
Ligand information
>7bah Chain D (length=12) [
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gacgcuagcguc
............
Receptor-Ligand Complex Structure
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PDB
7bah
A conserved isoleucine in the RNA sensor RIG-I controls immune tolerance to mitochondrial RNA
Resolution
1.89 Å
Binding residue
(original residue number in PDB)
C829 H830 F853 I875 V886 K888
Binding residue
(residue number reindexed from 1)
C28 H29 F52 I74 V85 K87
Enzymatic activity
Enzyme Commision number
3.6.4.13
: RNA helicase.
External links
PDB
RCSB:7bah
,
PDBe:7bah
,
PDBj:7bah
PDBsum
7bah
PubMed
UniProt
O95786
|RIGI_HUMAN Antiviral innate immune response receptor RIG-I (Gene Name=RIGI)
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