Structure of PDB 6xb8 Chain B Binding Site BS02

Receptor Information
>6xb8 Chain B (length=200) Species: 648242 (Adeno-associated virus 2 Srivastava/1982) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MPGFYEIVIKVPSDLDEHLPGISDSFVNWVAEKEWELPPDSDMDLNLIEQ
APLTVAEKLQRDFLTEWRRVSKAPEALFFVQFEKGESYFHMHVLVETTGV
KSMVLGRFLSQIREKLIQRIYRGIEPTLPNWFAVTKTRNGAGGGNKVVDE
SYIPNYLLPKTQPELQWAWTNMEQYLSACLNLTERKRLVAQHLTHVSQTQ
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6xb8 Chain B Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6xb8 The Cryo-EM structure of AAV2 Rep68 in complex with ssDNA reveals a malleable AAA+ machine that can switch between oligomeric states.
Resolution3.3 Å
Binding residue
(original residue number in PDB)		E83 H92
Binding residue
(residue number reindexed from 1)		E83 H92
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
External links
PDB RCSB:6xb8, PDBe:6xb8, PDBj:6xb8
PDBsum6xb8
PubMed33270897
UniProtP03132|REP68_AAV2S Protein Rep68 (Gene Name=Rep68)

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