Structure of PDB 6vv5 Chain B Binding Site BS02

Receptor Information
>6vv5 Chain B (length=1097) Species: 28295 (Porcine epidemic diarrhea virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NFRRFFSKFNVQAPAVVVLGGYLPIVHGIFVSGFEIGISQPSGYQLYLHK
ATTARLRICQFPSNCLFNKAIPAHVVGITWDNDRVTVFSDKIYYFYFKND
WSRVATAMQYVYEPTYYMLNVTSAGEDGISYQPCTANCIGYAANVFATEP
NGHIPEGFSFNNWFLLSNDSTLVHGKVVSNQPLLVNCLLAIPKIYQFFSF
NQTIDGVCNGAAVQRAPEALRFNINDISVILASIVLHTALGTNFSFVCSN
SSNPHLATPYYCFLKVDTYNSTVYKFLAVLPPTVREIVITKYGDVYVNGF
GYLHLGLLDAVTINFTGFWTIASTNFVDALIEVQGTAIQRILYCDDPVSQ
LKCSQVAFDLDDGFYTISSREQPISFVTLPSFNDHSFVNITVSASFGANL
IASDTTINGFSSFCVDTRQFTISLFYNVTNVSKSQDSNCPFTLQSVNDYL
SFSKFCVSTSLLASACTIDLFGYPESGVKFTSLYFQFTKGELITGTPKPF
EGVTDVSFMTLDVCTKYTIYGFKGEGIITLTNSSFLAGVYYTSDSGQLLA
FKNVTSGAVYSVTPCSFSEQAAYVDDDIVGVISSLSSSTFNSTRELPGFF
YHSNDGSNCTEPVLVYSNIGVCKSGSIGYVPSQSGQVKIAPTVTGNISIP
TNFSMSIRTEYLQLYNTPVSVDCATYVCNGNSRCKQLLTQYTAACKTIES
ALQLSARLESVEVNSMLTISDEALQLATISSFNGDGYNFTNVLGVSVVQK
RSFIEDLLFNKVVDEDYKRCSNGRSVADLVCAQYYSGVMVLPGVVDAEKL
HMYSASLIGGMVLGGFTSAAALPFSYAVQARLNYLALQTDVLQRNQQLLA
ESFNSAIGNITSAFESVKEAISQTSKGLNTVAHALTKVQEVVNSQGAALT
QLTVQLQHNFQAISSSIDDIYSRLDILSADAQVDRLITGRLSALNAFVAQ
TLTKYTEVQASRKLAQQKVNECVKSQSQRYGFCGGDGEHIFSLVQAAPQG
LLFLHTVLVPSDFVDVIAIAGLCVNDEIALTLREPGLVLFTHEEYFVSSR
RMFEPRKPTVSDFVQIESCVVTYVNLTRDQLPDVIPDYIDVNKTLDE
Ligand information
Ligand IDPAM
InChIInChI=1S/C16H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18/h7-8H,2-6,9-15H2,1H3,(H,17,18)/b8-7-
InChIKeySECPZKHBENQXJG-FPLPWBNLSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0CCCCCC\C=C/CCCCCCCC(=O)O
ACDLabs 10.04O=C(O)CCCCCCC\C=C/CCCCCC
CACTVS 3.341CCCCCCC=CCCCCCCCC(O)=O
OpenEye OEToolkits 1.5.0CCCCCCC=CCCCCCCCC(=O)O
CACTVS 3.341CCCCCC\C=C/CCCCCCCC(O)=O
FormulaC16 H30 O2
NamePALMITOLEIC ACID
ChEMBLCHEMBL453509
DrugBankDB04257
ZINCZINC000008221009
PDB chain6vv5 Chain A Residue 1407 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6vv5 Structure and immune recognition of the porcine epidemic diarrhea virus spike protein.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		R842 L941 P942
Binding residue
(residue number reindexed from 1)		R707 L791 P792
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0019062 virion attachment to host cell
GO:0019064 fusion of virus membrane with host plasma membrane
GO:0039654 fusion of virus membrane with host endosome membrane
GO:0046718 symbiont entry into host cell
GO:0046813 receptor-mediated virion attachment to host cell
GO:0075509 endocytosis involved in viral entry into host cell
Cellular Component
GO:0016020 membrane
GO:0019031 viral envelope
GO:0033644 host cell membrane
GO:0044173 host cell endoplasmic reticulum-Golgi intermediate compartment membrane
GO:0055036 virion membrane

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6vv5, PDBe:6vv5, PDBj:6vv5
PDBsum6vv5
PubMed33378641
UniProtS5RJN4

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