Structure of PDB 6v4p Chain B Binding Site BS02

Receptor Information
>6v4p Chain B (length=375) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQV
EDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFV
DKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEV
KKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIA
LDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLI
FAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVEL
EVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCP
QEKEKSFTIKPVGFKDSLIVQVTFD
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain6v4p Chain B Residue 702 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6v4p Cryo-Electron Microscopy Structure of the alpha IIb beta 3-Abciximab Complex.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		S123 D126 D127 M335
Binding residue
(residue number reindexed from 1)		S66 D69 D70 M278
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:6v4p, PDBe:6v4p, PDBj:6v4p
PDBsum6v4p
PubMed31969014
UniProtP05106|ITB3_HUMAN Integrin beta-3 (Gene Name=ITGB3)

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