Structure of PDB 6uw1 Chain B Binding Site BS02

Receptor Information
>6uw1 Chain B (length=319) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKITVLVGGVGGARFLLGVQNLLGLGSFADGPSKHELTAVVNIGDDAWMH
GVRICPDLDTCMYTLGGGIDPDRGWGHRNETWNAKEELAAYGVQPDWFGL
GDRDLATHLVRSQMLRAGYPLSQVTEALCKRWQPGARLLPASDERSETHV
VITDPTDGERRAIHFQEWWVRYRAKVPTHSFAYVGADQATAGPGVVEAIG
DADIVLLAPSNPVVSIGPILQIPGIRGALRSTSAPVIGYSPIIAADECLK
VIGVESTSQAVGEFFGARAGTGLLDGWLVHEGDHAQIEGVKVKAVPLLMT
DPEATAAMVRAGLDLAGVS
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain6uw1 Chain B Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6uw1 Cellular and Structural Basis of Synthesis of the Unique Intermediate Dehydro-F420-0 in Mycobacteria.
Resolution2.205 Å
Binding residue
(original residue number in PDB)		E144 Q188
Binding residue
(residue number reindexed from 1)		E144 Q188
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.8.28: 2-phospho-L-lactate transferase.
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0016740 transferase activity
GO:0043743 LPPG:FO 2-phospho-L-lactate transferase activity

View graph for
Molecular Function
External links
PDB RCSB:6uw1, PDBe:6uw1, PDBj:6uw1
PDBsum6uw1
PubMed32430409
UniProtA0QTG2|FBIA_MYCS2 Phosphoenolpyruvate transferase (Gene Name=fbiA)

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