Structure of PDB 6tu2 Chain B Binding Site BS02

Receptor Information
>6tu2 Chain B (length=314) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RGTITDASGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILL
SFKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDVYEIKEAIKGAGT
DEACLIEILASRSNEHIRELNRAYKTEFKKTLEEAIRSDTSGHFQRLLIS
LSQGNRDESTNVDMSLVQRDVQELYAAGENRLGTDESKFNAILCSRSRAH
LVAVFNEYQRMTGRDIEKSICREMSGDLEQGMLAVVKCLKNTPAFFAERL
NKAMRGAGTKDRTLIRIMVSRSELDLLDIRAEYKRMYGKSLYHDITGDTS
GDYRKILLKICGGN
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain6tu2 Chain B Residue 602 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6tu2 Structure of the ALS Mutation Target Annexin A11 Reveals a Stabilising N-Terminal Segment.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		M211 G213 F214 G215 E255
Binding residue
(residue number reindexed from 1)		M23 G25 F26 G27 E67
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0005544 calcium-dependent phospholipid binding

View graph for
Molecular Function
External links
PDB RCSB:6tu2, PDBe:6tu2, PDBj:6tu2
PDBsum6tu2
PubMed32344647
UniProtQ5XI77

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