Structure of PDB 6szv Chain B Binding Site BS02

Receptor Information
>6szv Chain B (length=743) Species: 1129347 (Influenza A virus (A/little yellow-shouldered bat/Guatemala/060/2010(H17N10))) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDVNPMLIFLKVPVQNAISTTFPYTGDPPYSHGTGTGYTMDTVIRTHDYS
SRGIWKTNSETGAQQLNPIDGPLPEDNEPSGYAQTDCVLELIEGLDRSHP
GLFETACQETIDAIQQTRVDKLTQGRQTYDWTLNRNQPAATALANTIEVF
RKNGYKLNESGRLIDFLKDVLLSFENDSMEVTTHFQKKKRIRDNHSKKMI
TQRTIGKKRVKLTKKNYLIRALTLNTMTKDAERGKLKRRAIATPGMQIRG
FVYFVELLARNICERLEQSGLPVGGNEKKAKLANVIKKMMAKSTDEELSY
TITGDNTKWNENQNPRIFLAMVLRITAGQPEWFRDLLAVAPIMFSNKVAR
LGRGYMFESKSMHLRTQISAENLSDINLRYFNEDTKKKIEKIRHLMVEGT
ASLSPGMMMGMFNMLSTVLGVSVLNLGQREILKRTYWWDGLQSSDDFALI
INGHFKEDIQQGVNHFYRTCKLVGINMSQKKSYINKTGTFEFTSFFYRYG
FVANFSMELPSFGVAGNNESADMSIGTTVIKTNMINNDLGPATAQMAIQL
FIKDYRYTYRCHRGDTNLETRRTKSIKRLWTETISKAGLLVADGGPNPYN
LRNLHIPEVCLKWSLMDPDYRGRLCNPNNPFVHHMEVESTSLEYDAVATT
HSWTPKRNRSILNTNQRGILEDERIYQKCCQVFEKFFPSSTYRRPIGMAS
MLDAMLSRARIDARIDLESGRISSQDFSEITNTCKAIEALKRQ
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6szv A Structure-Based Model for the Complete Transcription Cycle of Influenza Polymerase.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		G125 R126 Q127 R135 N136 M227 I241 A242 T243 R249 R260 P272 R353 G410 M414 I525 T528 H633 T667 K669 R670 S673 R687 Q690 Q694
Binding residue
(residue number reindexed from 1)		G125 R126 Q127 R135 N136 M227 I241 A242 T243 R249 R260 P272 R353 G410 M414 I525 T528 H633 T654 K656 R657 S660 R674 Q677 Q681
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003723 RNA binding
GO:0003968 RNA-dependent RNA polymerase activity
GO:0034062 5'-3' RNA polymerase activity
Biological Process
GO:0001172 RNA-templated transcription
GO:0019083 viral transcription
GO:0039523 symbiont-mediated suppression of host mRNA transcription via inhibition of RNA polymerase II activity
GO:0039694 viral RNA genome replication
Cellular Component
GO:0005737 cytoplasm
GO:0030430 host cell cytoplasm
GO:0042025 host cell nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6szv, PDBe:6szv, PDBj:6szv
PDBsum6szv
PubMed32304664
UniProtH6QM91

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