Structure of PDB 6snv Chain B Binding Site BS02

Receptor Information
>6snv Chain B (length=222) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GKTITDFSISRSVLAKYEVINQVDKKFILIRCQSIHNCLLVLVDQHACDE
RIRLEELFYSLLTEVVTGTFVARDLKDCCIEVDRTEADLFKHYQSEFKKW
GIGYETIETSLLEIKTLPEMLTSKYNGDKDYLKMVLLQHAHDLKDFKKLP
MDLSHFKLYWWKYSSCVPTVFHEILNSKACRSAVMFGDELTRQECIILIS
KLSRCHNPFECAHGRPSMVPIA
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6snv Chain B Residue 902 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6snv Molecular basis of the dual role of the Mlh1-Mlh3 endonuclease in MMR and in meiotic crossover formation.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		E529 C701 H703
Binding residue
(residue number reindexed from 1)		E50 C211 H213
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0140664 ATP-dependent DNA damage sensor activity
Biological Process
GO:0006298 mismatch repair
Cellular Component
GO:0032300 mismatch repair complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6snv, PDBe:6snv, PDBj:6snv
PDBsum6snv
PubMed34088835
UniProtQ12083|MLH3_YEAST DNA mismatch repair protein MLH3 (Gene Name=MLH3)

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