Structure of PDB 6sj3 Chain B Binding Site BS02

Receptor Information
>6sj3 Chain B (length=503) Species: 1470557 (Streptomyces sp. Tu 6176) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TENLYFQGAMGARLITGGTVYTADAQESVHARGAVLTVDDKVVAVGPAVE
VEQAVQALDPAVRAELRRLDASRMMVLPGFVNAHWHEMFAMGFTMRGALR
PPSDRADQVAFMGGGGDMHQISATFDRFDGLIEAMTEDEARAIAEYSMWI
QLRGGVTTLGDMGSLNRPLAMVEAARRLGMRFSASTWASDAVLAPDRSRF
LRTRDADTVLASFEALLGAVAADPTGRIRCRPNVSYVTNMTDELARGMAE
LVERHDLPFATHVGALRNEADAMRAYHGETGVRRLAEAGLVDERLMAGHS
AFLDDQEQKLMLAGRAHISHSPGKYGPSGESALTETGVVPALRRAGLDVS
LSTDAAALPGAGIAETMRAAWQMYNEMSADQTEVLPTDALAMATRIAAKG
LRWDDAVGSLEPGKQADLLLVRTDDWRYLLNPRPLESFLWLAGSADVDTV
IVGGRTLVEGGRGVEVDEAALRDRYLQALRGFTTRALRVPAEAVDPVLAE
VAR
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6sj3 Chain B Residue 505 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6sj3 The Biosynthesis of the Benzoxazole in Nataxazole Proceeds via an Unstable Ester and has Synthetic Utility.
Resolution1.17 Å
Binding residue
(original residue number in PDB)		H75 H77 H253 D345
Binding residue
(residue number reindexed from 1)		H84 H86 H262 D354
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:6sj3, PDBe:6sj3, PDBj:6sj3
PDBsum6sj3
PubMed31903677
UniProtA0A022MQ12

[Back to BioLiP]