Structure of PDB 6rw3 Chain B Binding Site BS02

Receptor Information
>6rw3 Chain B (length=439) Species: 5833 (Plasmodium falciparum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FFSTSFKYVLSACIASFIFGYQVSVLNTIKNFIVVEFECSNNTIQSSFLL
ASVFIGAVLGCGFSGYLVQFGRRLSLLIIYNFFFLVSILTSITHHFHTIL
FARLLSGFGIGLVTVSVPMYISEMTHKDKKGAYGVMHQLFITFGIFVAVM
LGLAMGEGPKTSFAKLWWRLMFLFPSVISLIGILALVVFFKEETPYFLFE
KGRIEESKNILKKIYETDNVDEPLNAIKEAVEQNESAKKNSLSLLSALKI
PSYRYVIILGCLLSGLQQFTGINVLVSNSNELYKEFLDSHLITILSVVMT
AVNFLMTFPAIYIVEKLGRKTLLLWGCVGVLVAYLPTAIANEINNFVKIL
SIVATFVMIISFAVSYGPVLWIYLHEMFPSEIKDSAASLASLVNWVCAII
VVFPSDIIIKKSPSILFIVFSVMSILTFFFIFFFIKETK
Ligand information
Ligand IDBGC
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6-/m1/s1
InChIKeyWQZGKKKJIJFFOK-VFUOTHLCSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.6C(C1C(C(C(C(O1)O)O)O)O)O
CACTVS 3.370OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O
CACTVS 3.370OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
OpenEye OEToolkits 1.7.6C([C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)O)O)O)O)O
ACDLabs 12.01OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namebeta-D-glucopyranose;
beta-D-glucose;
D-glucose;
glucose
ChEMBLCHEMBL1614854
DrugBankDB02379
ZINCZINC000003833800
PDB chain6rw3 Chain B Residue 602 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6rw3 The molecular basis for sugar import in malaria parasites.
Resolution3.65 Å
Binding residue
(original residue number in PDB)		Q169 Q305 I310 N311 W412
Binding residue
(residue number reindexed from 1)		Q138 Q267 I272 N273 W371
Annotation score5
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0015149 hexose transmembrane transporter activity
GO:0022857 transmembrane transporter activity
Biological Process
GO:0008645 hexose transmembrane transport
GO:0015749 monosaccharide transmembrane transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6rw3, PDBe:6rw3, PDBj:6rw3
PDBsum6rw3
PubMed31996846
UniProtO97467

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