Structure of PDB 6q0r Chain B Binding Site BS02

Receptor Information
>6q0r Chain B (length=208) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EHVLKQLERVKISGQLSPRLFRKLPPRVCVSLKNIVDEDFLYAGHIFLGF
SKCGRYVLSYTSSSSFYIYHLYWWEFNVHSKLKLVRQVRLFQDEEIYSDL
YLTVCEWPSDASKVIVFGFNTRSANMMSDENHRDIYVSTVAVPPPGRCAA
CQDASRAAQCLRHGFMLHTKYQVVYPFPTFQPAFQLKKDQVVLLNTSYSL
VACAVSVH
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6q0r Chain B Residue 303 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6q0r Structural complementarity facilitates E7820-mediated degradation of RBM39 by DCAF15.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		C193 C196 C211 H214
Binding residue
(residue number reindexed from 1)		C148 C151 C160 H163
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0016567 protein ubiquitination

View graph for
Biological Process
External links
PDB RCSB:6q0r, PDBe:6q0r, PDBj:6q0r
PDBsum6q0r
PubMed31686031
UniProtQ66K64|DCA15_HUMAN DDB1- and CUL4-associated factor 15 (Gene Name=DCAF15)

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