Structure of PDB 6ny6 Chain B Binding Site BS02

Receptor Information

>6ny6 Chain B (length=236) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

ITVKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERT
FRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTN
FKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRL
LKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGN
DDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

6ny6 Chain B Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6ny6 Monomeric YoeB toxin retains RNase activity but adopts an obligate dimeric form for thermal stability.
Resolution	3.74 Å
Binding residue (original residue number in PDB)	K74 D166 K169 D191 D205
Binding residue (residue number reindexed from 1)	K70 D162 K165 D187 D201
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome
GO:0019843	rRNA binding

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome
GO:0015935	small ribosomal subunit
GO:0022627	cytosolic small ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:6ny6, PDBe:6ny6, PDBj:6ny6
PDBsum	6ny6
PubMed	31501867
UniProt	P80371\|RS2_THET8 Small ribosomal subunit protein uS2 (Gene Name=rpsB)

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