Structure of PDB 6nie Chain B Binding Site BS02

Receptor Information
>6nie Chain B (length=244) Species: 1003195 (Streptantibioticus cattleyicolor NRRL 8057 = DSM 46488) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LKDVCAPLEKDDIRRLSQAFHRFGIVTVTELIEPHTRKLVRAEADRLLDQ
YAERRDLRLATTDYTRRSMSVVPSETIAANSELVTGLYAHRELLAPLEAI
AGERLHPCPKADEEFLITRQEQRGDTHGWHWGDFSFALIWVLQAPPIDVG
GLLQCVPHTTWDKASPQINRYLVENPIDTYHFESGDVYFLRTDTTLHRTI
PLREDTTRIILNMTWAGERDLSRKLAADDRWWDNAEVSAARAIK
Ligand information
Ligand IDFE2
InChIInChI=1S/Fe/q+2
InChIKeyCWYNVVGOOAEACU-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Fe+2]
CACTVS 3.341[Fe++]
FormulaFe
NameFE (II) ION
ChEMBL
DrugBankDB14510
ZINC
PDB chain6nie Chain B Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6nie A family of radical halogenases for the engineering of amino-acid-based products.
Resolution1.95 Å
Binding residue
(original residue number in PDB)		H137 H204
Binding residue
(residue number reindexed from 1)		H130 H197
Annotation score1
Enzymatic activity
Enzyme Commision number 1.14.20.-
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0062147 L-lysine 4-chlorinase activity
Biological Process
GO:0008652 amino acid biosynthetic process
GO:0017000 antibiotic biosynthetic process
GO:0062142 L-beta-ethynylserine biosynthetic process
GO:0062143 L-propargylglycine biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6nie, PDBe:6nie, PDBj:6nie
PDBsum6nie
PubMed31548692
UniProtG8XHD5|BESD_STREN L-lysine 4-chlorinase (Gene Name=besD)

[Back to BioLiP]