Structure of PDB 6mat Chain B Binding Site BS02

Receptor Information
>6mat Chain B (length=578) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RTPPTKVSILDIAGVDDTLQRLLKEVWFPLRGGEACEKMGYRYDNGVLLH
GPSGCGKTTLAHAIAGSIGVAFIPVSAPSVIGGTSGESEKNIRDVFDEAI
RLAPCLIFLDQIDAIAGRRESANKGMESRIVAEIMNGMDRIRQNTPLGKN
VVVLAATNRPEFLDPAIRRRFSVEIDMGMPSERAREQILRSLTRDLSLAD
DINFKELAKMTPGYVGSDLQYVVKAAVSESFQANIDSLLAQARAKHPADH
LANVSQPQRDWLLLEAHRDEEVSWPSTKITMEQFRKAVSLVQPASKREGF
STIPDTTWSHVGALEDVRKKLEMSIIGPIKNPELFTRVGIKPAAGILLWG
PPGCGKTLVAKAVANESKANFISIKGPELLNKYVGESERAVRQLFSRAKS
SAPCILFFDQMDALVPRRDDSLSDASARVVNTLLTELDGVGDRSGIYVIG
ATNRPDMIDEAIRRPGRLGTSIYVGLPSAEDRVKILKTLYRNTVQGTTDA
DLEKVALDLRCTGFSGADLGNLMQAAAQACLERVYTQRQQKRKEGEEEIE
PVITMEDWEKALNEVKPSVKDPEKYMHS
Ligand information
Ligand IDATP
InChIInChI=1S/C10H16N5O13P3/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1
InChIKeyZKHQWZAMYRWXGA-KQYNXXCUSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0c1nc(c2c(n1)n(cn2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N
CACTVS 3.341Nc1ncnc2n(cnc12)[CH]3O[CH](CO[P](O)(=O)O[P](O)(=O)O[P](O)(O)=O)[CH](O)[CH]3O
ACDLabs 10.04O=P(O)(O)OP(=O)(O)OP(=O)(O)OCC3OC(n2cnc1c(ncnc12)N)C(O)C3O
OpenEye OEToolkits 1.5.0c1nc(c2c(n1)n(cn2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO[P@@](=O)(O)O[P@](=O)(O)OP(=O)(O)O)O)O)N
CACTVS 3.341Nc1ncnc2n(cnc12)[C@@H]3O[C@H](CO[P@](O)(=O)O[P@@](O)(=O)O[P](O)(O)=O)[C@@H](O)[C@H]3O
FormulaC10 H16 N5 O13 P3
NameADENOSINE-5'-TRIPHOSPHATE
ChEMBLCHEMBL14249
DrugBankDB00171
ZINCZINC000004261765
PDB chain6mat Chain B Residue 901 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6mat Cryo-EM structure of the essential ribosome assembly AAA-ATPase Rix7.
Resolution4.5 Å
Binding residue
(original residue number in PDB)		H502 G545 C546 G547 K548 T549 L550 N645
Binding residue
(residue number reindexed from 1)		H310 G353 C354 G355 K356 T357 L358 N453
Annotation score5
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:1990275 preribosome binding
Biological Process
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6mat, PDBe:6mat, PDBj:6mat
PDBsum6mat
PubMed30705282
UniProtG0RZG1

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