Structure of PDB 6m5r Chain B Binding Site BS02

Receptor Information
>6m5r Chain B (length=689) Species: 10299 (Human alphaherpesvirus 1 strain 17) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AAPVSEPTVARQKLLALLGQVQTYVFQIELLRRCDPHIGRGKLPQLKLNA
LQVRALRRRLRPGLEAQAGAFLTPLSVTLELLLEYAWREGERLLGSLETF
ATAGDVAAFFTETMGLARPCPYHQRVRLDTYGGTVHMELCFLHDVENFLK
QLNYCHLITPSRGATAALERVREFMVGAVGSGLIVPPELSDPSHPCAVCF
EELCVTANQGATIASRLADRICNHVTQQAQVRLDANELRRYLPHAAGLSD
ADRARALSVLDHALARYAISELQFWLASGDRAGQTTMDAFASNLTALARR
ELQQETAAVAVELALFGRRAEHFDRAFGSHLAALDMVDALIIGGQATSPD
DQIEALIRACYDHHLTTPLLRRLVSPEQCDEEALRRVLARMGAGGQGPET
WGDIATQAAADVRERRRLYADRLTKRSLASLGRCVREQRGELEKMLRVSV
HGEVLPATFAAVANGFAARARFCALTAGAGTVIDNRSAPGVFDAHRFMRA
SLLRHQVDPALLPSITHRFFELVNGPLFDHSTHSFAQPPNTALYYSVENV
GLLPHLKEELARFIMGASGADWAVSEFQRFYCFDGISGITPTQRAAWRYI
RELIIATTLFASVYRCGELELRRPDCSRPTSEGRYRYPPGVYLTYDSDCP
LVAIVESAPDGCIGPRSVVVYDRDVFSILYSVLQHLAPR
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6m5r Chain B Residue 802 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6m5r Architecture of the herpesvirus genome-packaging complex and implications for DNA translocation.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		C200 C223 H225
Binding residue
(residue number reindexed from 1)		C199 C222 H224
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0046872 metal ion binding
Biological Process
GO:0019073 viral DNA genome packaging
Cellular Component
GO:0042025 host cell nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6m5r, PDBe:6m5r, PDBj:6m5r
PDBsum6m5r
PubMed32328903
UniProtP10212|TRM1_HHV11 Tripartite terminase subunit 1 (Gene Name=TRM1)

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