Structure of PDB 6m2v Chain B Binding Site BS02
Receptor Information
>6m2v Chain B (length=196) Species:
10090
(Mus musculus) [
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IVPANHFGPIPGVPVGTMWRFRVQVSESGVHRPHVAGIHGRSNDGAYSLV
LAGGYEDDVDNGNYFTYTGSGGSSDQKLTNNNRALALNCHSPINEKGAEA
EDWRQGKPVRVVRNMKGGKHSKYAPAEGNRYDGIYKVVKYWPERSGFLVW
RYLLRRDDTEPEPWTREGKDRTRQLGLTMQYPEGYLEALANKEKSR
Ligand information
>6m2v Chain D (length=13) [
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tcacgctgcgtga
Receptor-Ligand Complex Structure
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PDB
6m2v
Mechanistic insights into recognition of symmetric methylated cytosines in CpG and non-CpG DNA by UHRF1 SRA.
Resolution
3.0 Å
Binding residue
(original residue number in PDB)
F437 R438 V451 A452 G453 A468 G470 Y471 Y483 T484 K544
Binding residue
(residue number reindexed from 1)
F21 R22 V35 A36 G37 A52 G54 Y55 Y67 T68 K116
Enzymatic activity
Enzyme Commision number
2.3.2.27
: RING-type E3 ubiquitin transferase.
External links
PDB
RCSB:6m2v
,
PDBe:6m2v
,
PDBj:6m2v
PDBsum
6m2v
PubMed
33359809
UniProt
Q8VDF2
|UHRF1_MOUSE E3 ubiquitin-protein ligase UHRF1 (Gene Name=Uhrf1)
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