Structure of PDB 6l3s Chain B Binding Site BS02

Receptor Information

>6l3s Chain B (length=218) Species: 582 (Morganella morganii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

LPNLRVEKLEEGVYVHTSYEEVKGWGVVTKHGLVVLIGADAYLIDTPFTA
KDTEKLVNWFVERGYKIKGTVSSHFHSDSTGGIEWLNSQSIPTYASELTN
ELLKKDGKVQAKNSFDGVSYWLAKDKIEVFYPGPGHTQDNVVVWLPEKEI
LFGGCFVKPHGLGNLGDANLEAWPESAKILMEKYGKAKLVVSGHSETGDA
THLKRTWEQAVKGLKESK

Ligand information

Ligand ID

InChI

InChI=1S/Zn/q+2

InChIKey

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Name

ZINC ION

PDB chain

6l3s Chain B Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	6l3s Crystal structure of the metallo-beta-lactamase IMP-27
Resolution	1.7 Å
Binding residue (original residue number in PDB)	H95 H97 H157
Binding residue (residue number reindexed from 1)	H74 H76 H136
Annotation score	1

Enzymatic activity

Catalytic site (original residue number in PDB)	H95 H97 D99 H157 C176 K179 N185 H215
Catalytic site (residue number reindexed from 1)	H74 H76 D78 H136 C155 K158 N164 H194
Enzyme Commision number	3.5.2.6: beta-lactamase.

Gene Ontology

	Molecular Function
GO:0008270	zinc ion binding
GO:0008800	beta-lactamase activity
GO:0016787	hydrolase activity
GO:0046872	metal ion binding

	Biological Process
GO:0017001	antibiotic catabolic process
GO:0046677	response to antibiotic

	Cellular Component
GO:0042597	periplasmic space

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:6l3s, PDBe:6l3s, PDBj:6l3s
PDBsum	6l3s
PubMed
UniProt	A0A286S0G7

[Back to BioLiP]