Structure of PDB 6kuv Chain B Binding Site BS02

Receptor Information
>6kuv Chain B (length=705) Species: 1173138 (Influenza D virus (D/swine/Oklahoma/1334/2011)) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MEINPYLLMLNNDITSMISLTYPYTGAPPMSHGTSTKYSMETVSRTYSYS
RTKKEVPSGIFPIERRKFCNTIEDKENLEKPNGNVDINFMLSLAEMLEEK
MGKGFFKFCANEAEAEILKMHFSKLTEGRQTYDWTSERNMPAATALQLTV
DAIQETQGTFKGTTMVEYCNKILEMMDWPEVKFKKVTLMITKIGREEFIK
RICTINTMAKDGERGKYKRRAIATPGMGIRPFSKIVETLAQKICERLAES
GLPVEKKAKLKTTVSSTNSKLQEGQFMVNITGDNSKWNECQQPEAYLAML
AYITKDSSNLMKDLCSVAPTLFCNKYVKMGQGFRAKNKRKTKEIVIPAKK
MKERKELMNAEWRDLFETIEPYMDGECCFLGGGMLMGMFNMLSTVFGVMT
LNYREERNCYWTGLQSSDDFVLFCISRTWPEMEMTILKFIAVCKLMGINM
SLEKSYGCLPELFEFTSMFFSGDFVSNIALELPAFTTAGMNEGTDFTAAM
SVIRTNMINNGLSPGTALMALRICLQEFRATYRVHPYDSGVKNHRMKIIR
KFIETIENKDGLLISDGGKLMNNISSLHIPEEILKEDLMDPSYRNRVFNP
RNPFTQFAVVSTHSFRTRSNRTLLNTDMRAMALEEKRYQVVCNMYRSVFE
SADVNTPIGSMSMGEAIEAKILDRARTQFENGIIGGEEYSEIKRLIEDAK
RQRLS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6kuv Structural insight into RNA synthesis by influenza D polymerase.
Resolution4.1 Å
Binding residue
(original residue number in PDB)		H32 T34 K37 K239 R358 W386
Binding residue
(residue number reindexed from 1)		H32 T34 K37 K218 R334 W362
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003723 RNA binding
GO:0003968 RNA-dependent RNA polymerase activity
GO:0034062 5'-3' RNA polymerase activity
Biological Process
GO:0001172 RNA-templated transcription
GO:0006351 DNA-templated transcription
GO:0019079 viral genome replication
GO:0039694 viral RNA genome replication

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Molecular Function
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Biological Process
External links
PDB RCSB:6kuv, PDBe:6kuv, PDBj:6kuv
PDBsum6kuv
PubMed31209309
UniProtK9LH03

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