Structure of PDB 6kun Chain B Binding Site BS02

Receptor Information
>6kun Chain B (length=294) Species: 39946 (Oryza sativa Indica Group) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EIPAIDLRLAGGGGGAEETARLRDACARLGCFRVSGHGVPPGLQAEMKAA
VRALFDLPDDAKRRNADIIPGSGYVPPPLYEAFGLCDAAAPADVDAFCAR
LDAPPHVRETVKAYAERMHSLIVDVAGKVAASLGLHGASFQDWPCQFRMN
RYNYTQDSVGSPGVQVHTDSGFLTVLQEDECVGGLEVLDPAAGEFVPVDP
LPGSFVVNVGDVGQAWSNGRLHNVKHRVQCVAAVPRVSIAMFLLAPKDDT
VSAPGELVDGEHPRRYREFKYDDYRRLRLSTGERAGEALARLAA
Ligand information
Ligand IDIAC
InChIInChI=1S/C10H9NO2/c12-10(13)5-7-6-11-9-4-2-1-3-8(7)9/h1-4,6,11H,5H2,(H,12,13)
InChIKeySEOVTRFCIGRIMH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.6c1ccc2c(c1)c(c[nH]2)CC(=O)O
ACDLabs 12.01O=C(O)Cc2c1ccccc1nc2
CACTVS 3.370OC(=O)Cc1c[nH]c2ccccc12
FormulaC10 H9 N O2
Name1H-INDOL-3-YLACETIC ACID;
INDOLE ACETIC ACID
ChEMBLCHEMBL82411
DrugBankDB07950
ZINCZINC000000083860
PDB chain6kun Chain B Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6kun A common allosteric mechanism regulates homeostatic inactivation of auxin and gibberellin.
Resolution2.002 Å
Binding residue
(original residue number in PDB)		R154 S176 R281 R284 R290
Binding residue
(residue number reindexed from 1)		R148 S170 R275 R278 R284
Annotation score4
Enzymatic activity
Enzyme Commision number 1.14.11.-
Gene Ontology
Molecular Function
GO:0016706 2-oxoglutarate-dependent dioxygenase activity
GO:0046872 metal ion binding
GO:0051213 dioxygenase activity
Biological Process
GO:0009852 auxin catabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6kun, PDBe:6kun, PDBj:6kun
PDBsum6kun
PubMed32358569
UniProtQ01IX6|DAO_ORYSI 2-oxoglutarate-dependent dioxygenase DAO (Gene Name=DAO)

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