Structure of PDB 6kuk Chain B Binding Site BS02

Receptor Information
>6kuk Chain B (length=701) Species: 1173138 (Influenza D virus (D/swine/Oklahoma/1334/2011)) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MEINPYLLMLNNDITSMISLTYPYTGAPPMSHGTSTKYSMETVSRTYSYS
RTKKEVPSGIFPIERRKFCNTIEDKENLEKPNGNVDINFMLSLAEMLEEK
MGKGFFKFCANEAEAEILKMHFSKLTEGRQTYDWTSERNMPAATALQLTV
DAIQETQGTFKGTTMVEYCNKILEMMDWPEVKFKKVTLMITKIGREEFIK
RICTINTMAKDGERGKYKRRAIATPGMGIRPFSKIVETLAQKICERLAES
GKKAKLKTTVSSTNSKLQEGQFMVNITGDNSKWNECQQPEAYLAMLAYIT
KDSSNLMKDLCSVAPTLFCNKYVKMGQGFRAKNKRKTKEIVIPAKKMKER
KELMNAEWRDLFETIEPYMDGECCFLGGGMLMGMFNMLSTVFGVMTLNYR
EERNCYWTGLQSSDDFVLFCISRTWPEMEMTILKFIAVCKLMGINMSLEK
SYGCLPELFEFTSMFFSGDFVSNIALELPAFTTAGMNEGTDFTAAMSVIR
TNMINNGLSPGTALMALRICLQEFRATYRVHPYDSGVKNHRMKIIRKFIE
TIENKDGLLISDGGKLMNNISSLHIPEEILKEDLMDPSYRNRVFNPRNPF
TQFAVVSTHSFRTRSNRTLLNTDMRAMALEEKRYQVVCNMYRSVFESADV
NTPIGSMSMGEAIEAKILDRARTQFENGIIGGEEYSEIKRLIEDAKRQRL
S
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6kuk Structural insight into RNA synthesis by influenza D polymerase.
Resolution3.9 Å
Binding residue
(original residue number in PDB)
H32 K37 K239 R358 W386
Binding residue
(residue number reindexed from 1)
H32 K37 K218 R330 W358
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003723 RNA binding
GO:0003968 RNA-dependent RNA polymerase activity
GO:0034062 5'-3' RNA polymerase activity
Biological Process
GO:0001172 RNA-templated transcription
GO:0006351 DNA-templated transcription
GO:0019079 viral genome replication
GO:0039694 viral RNA genome replication

View graph for
Molecular Function

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Biological Process
External links
PDB RCSB:6kuk, PDBe:6kuk, PDBj:6kuk
PDBsum6kuk
PubMed31209309
UniProtK9LH03

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