Structure of PDB 6knc Chain B Binding Site BS02

Receptor Information
>6knc Chain B (length=1118) Species: 311400 (Thermococcus kodakarensis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PEMKAYFESLQREIDRAYAIARKARAQGKDPSFDVEVPQATDMAGRVESL
VGPPGVAERIRELVKEYGKEIAALKVVDEIIEGKFGDLGSKEKYAEQAVR
TALAILTEGIVSAPLEGIADVKIKRNEWADGSEYLALYYAGPIRSSGGTA
QALSVLVGDYVRRKLGLDRFKPSDEHIERMVEEVDLYHRAVTRLQYHPEA
DEVRLAMRNIPIEITGEETDKVEVSHRNVPGVETNHLRGGAILVLAEGVL
QKAKKLVKYIDKMGIEGWDWIKEFVEAKEKGVEKGFYYELYEKFRANIAP
NKKYTKEIIGGRPLFAEPSTNGGFRLRYGRSWSVNPATMLILGCIVTPAT
TVEGPIVRLKNGSVVRVDDYETALKVRNEVDEILYVGDALVNFGDFVENN
QTLLPANYVEEWWVQELVQAIKDLYEVELQPFAENDREAVEEAAEYLEVD
PDFLWNLLKDPLRVKPDVETAIHLSTVLDIPFHPYYTLYWNTLQPEEVEE
LQKALLGAQIEWAEFRKNRFAKKVVLENDKNIKRYLELLGLPHRLERVEK
KRKVIVVEYPWSAALLTPLGNLEWEFKAKPFYTVIDIINENNRIKLRDRG
ISWIGKPPVQVLFPIGLAGGQSRDIKKAAEEGKTARVEIAFFKCPKCGHV
GPEHLCPVCGTRKELLWHCPKCGADYPESDAKDFNYRCPKCDVELKPYAE
REIKPADLLRQAMDNVKVYGIDRLKGVKGMTSGYKMAEPLEKGLLRVKND
VYVFKDGTIRFDATDAPITHFKPKEIGTSVEKLRELGYTHDFEGKPLERD
DQILELKVQDVILPYEAGRYLLKVARFIDDLLEKFYGLPRFYNAEKMEDL
VGHLVIGLAPHTSAGIIGRIIGFSDVLVGYAHPYYHAAKRRNCDGDEDAV
MLLLDALLNFSKYYLPEKRGGKMDAPLVVTTRLDPREVDSEVHNMDVVRY
YPLEFYKATYELKSPKEVKVIERVEDGDMEEKVARQLALAERIRAVDEHH
VAETIINSHLVPDLRGNLRSFTRQEFRCVKCNTKYRRPPLTGKCPKCGGK
IVLTVSKGAIEKYLPTAKMLVTKYRVKDYTRQRICITEKDIKTLFQRTLM
GFSADICEKMVKERTGHS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6knc Two conformations of DNA polymerase D-PCNA-DNA, an archaeal replisome complex, revealed by cryo-electron microscopy.
Resolution9.3 Å
Binding residue
(original residue number in PDB)		S693 R794
Binding residue
(residue number reindexed from 1)		S622 R723
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
3.1.11.1: exodeoxyribonuclease I.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
Biological Process
GO:0006260 DNA replication

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6knc, PDBe:6knc, PDBj:6knc
PDBsum6knc
PubMed33115459
UniProtQ5JET0|DP2L_THEKO DNA polymerase II large subunit (Gene Name=polC)

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