Structure of PDB 6ki3 Chain B Binding Site BS02

Receptor Information
>6ki3 Chain B (length=300) Species: 561443 (African swine fever virus tick/South Africa/Pretoriuskop Pr4/1996) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SGGGMFGAFVSHRLWSDSGCTTTCITNSIANYVAFGEQIGFPFKSAQVFI
AGPRKAVINIQEDDKVELLKMIVKHNLWVVAHGTYLDVPWSRRSAFVTHF
IQQELLICKEVGIKGLVLHLGAVEPELIVEGLKKIKPVEGVVIYLETPHN
KHHTYKYSTMEQIKELFLRIRNTRLKQIGLCIDTAHIWSSGVNISSYNDA
GQWLRSLENIHSVIPPSHIMFHLNDAATECGSGIDRHASLFEGMIWKSYS
HKIKQSGLYCFVEYITRHQCPAILERNLGSSMQLQTALTAEFTTLKSLLK
Ligand information
Receptor-Ligand Complex Structure
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PDB6ki3 A unique DNA-binding mode of African swine fever virus AP endonuclease.
Resolution2.354 Å
Binding residue
(original residue number in PDB)		F5 S7 H8 F45 G48 P49 R50 Y81 H115 E142 H182 H233 E271 N273
Binding residue
(residue number reindexed from 1)		F9 S11 H12 F49 G52 P53 R54 Y85 H119 E146 H186 H237 E275 N277
Enzymatic activity
Enzyme Commision number 3.1.21.-
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity
GO:0004519 endonuclease activity
GO:0004527 exonuclease activity
GO:0008081 phosphoric diester hydrolase activity
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006281 DNA repair
GO:0006284 base-excision repair
Cellular Component
GO:0030430 host cell cytoplasm
GO:0042025 host cell nucleus
GO:0044423 virion component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6ki3, PDBe:6ki3, PDBj:6ki3
PDBsum6ki3
PubMed32194979
UniProtP0C9C6|APE_ASFP4 Probable AP endonuclease (Gene Name=Pret-146)

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