Structure of PDB 6k5h Chain B Binding Site BS02

Receptor Information
>6k5h Chain B (length=286) Species: 763924 (Phytophthora capsici LT1534) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
THSDGTVLHLGLRAGQVANRIVSVGSLGRAKVLAQLLDEGHFETFESARG
FTTYSGKVKGVPVSIVATGMGVPNMDFVVRETRAVVNGPMTIIRFGTCGA
VREEVPPGSVVVNGKGSIMVTRNPDAFFPGASEEDCYRVSRVMPSSSTLS
KALVASMEDKLTALRAEPVIAASSDCDALRVFDGLNATACSFYSSQGRLD
SNFDDRNEKLVEDLTTAHPDLYTVEMETFHLLDLAQRSRGSIQATAAVLV
VANRLSGQIVESEVLEALESFWGGVVLQTIVSTPLD
Ligand information
Ligand IDR1P
InChIInChI=1S/C5H11O8P/c6-1-2-3(7)4(8)5(12-2)13-14(9,10)11/h2-8H,1H2,(H2,9,10,11)/t2-,3-,4-,5-/m1/s1
InChIKeyYXJDFQJKERBOBM-TXICZTDVSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C([C@@H]1[C@H]([C@H]([C@H](O1)OP(=O)(O)O)O)O)O
OpenEye OEToolkits 1.5.0C(C1C(C(C(O1)OP(=O)(O)O)O)O)O
CACTVS 3.341OC[C@H]1O[C@H](O[P](O)(O)=O)[C@H](O)[C@@H]1O
CACTVS 3.341OC[CH]1O[CH](O[P](O)(O)=O)[CH](O)[CH]1O
ACDLabs 10.04O=P(OC1OC(C(O)C1O)CO)(O)O
FormulaC5 H11 O8 P
Name1-O-phosphono-alpha-D-ribofuranose;
RIBOSE-1-PHOSPHATE;
1-O-phosphono-alpha-D-ribose;
1-O-phosphono-D-ribose;
1-O-phosphono-ribose
ChEMBLCHEMBL603367
DrugBankDB03101
ZINCZINC000004228268
PDB chain6k5h Chain B Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6k5h Structural and catalytic analysis of two diverse uridine phosphorylases in Phytophthora capsici.
Resolution2.503 Å
Binding residue
(original residue number in PDB)		G35 R39 M80 R104 T107 F202 E235 M236 E237
Binding residue
(residue number reindexed from 1)		G25 R29 M70 R94 T97 F192 E225 M226 E227
Annotation score5
Enzymatic activity
Enzyme Commision number 2.4.2.3: uridine phosphorylase.
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004850 uridine phosphorylase activity
GO:0016757 glycosyltransferase activity
GO:0047847 deoxyuridine phosphorylase activity
Biological Process
GO:0006218 uridine catabolic process
GO:0009116 nucleoside metabolic process
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6k5h, PDBe:6k5h, PDBj:6k5h
PDBsum6k5h
PubMed32493959
UniProtA0A410UCT3

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