Structure of PDB 6jmv Chain B Binding Site BS02

Receptor Information
>6jmv Chain B (length=253) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NRSLIVTTLLEEPFVMFRKSDRTLYGNDRFEGYCIDLLKELAHILGFSYE
IRLVEDGKYGAQDDKGQWNGMVKELIDHKADLAVAPLTITHVREKAIDFS
KPFMTLGVSILYRKGTPIDSADDLAKQTKIEYGAVKDGATMTFFKKSKIS
TFEKMWAFMSSKPSALVKNNEEGIQRTLTADYALLMESTTIEYITQRNCN
LTQIGGLIDSKGYGIGTPMGSPYRDKITIAILQLQEEDKLHIMKEKWWRG
SGC
Ligand information
Ligand IDSYM
InChIInChI=1S/C6H11NO4/c1-3(5(8)9)2-4(7)6(10)11/h3-4H,2,7H2,1H3,(H,8,9)(H,10,11)/p-1/t3-,4+/m1/s1
InChIKeyKRKRAOXTGDJWNI-DMTCNVIQSA-M
SMILES
SoftwareSMILES
CACTVS 3.341C[CH](C[CH](N)C([O-])=O)C(O)=O
ACDLabs 10.04[O-]C(=O)C(N)CC(C(=O)O)C
OpenEye OEToolkits 1.5.0C[C@H](C[C@@H](C(=O)[O-])N)C(=O)O
CACTVS 3.341C[C@H](C[C@H](N)C([O-])=O)C(O)=O
OpenEye OEToolkits 1.5.0CC(CC(C(=O)[O-])N)C(=O)O
FormulaC6 H10 N O4
Name2S,4R-4-METHYLGLUTAMATE
ChEMBL
DrugBankDB03425
ZINC
PDB chain6jmv Chain B Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6jmv Structural and Functional Insights into GluK3-kainate Receptor Desensitization and Recovery.
Resolution1.832 Å
Binding residue
(original residue number in PDB)		Y61 T90 R95 G140 A141 T142 E189
Binding residue
(residue number reindexed from 1)		Y59 T88 R93 G138 A139 T140 E187
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:6jmv, PDBe:6jmv, PDBj:6jmv
PDBsum6jmv
PubMed31311973
UniProtP42264|GRIK3_RAT Glutamate receptor ionotropic, kainate 3 (Gene Name=Grik3)

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