Structure of PDB 6j7y Chain B Binding Site BS02

Receptor Information
>6j7y Chain B (length=165) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AQRMVWVDLEMTGLDIEKDQIIEMACLITDSDLNILAEGPNLIIKDWCKE
HHGKSGLTKAVKESTITLQQAEYEFLSFVRQQTPPGLCPLAGNSVHEDKK
FLDKYMPQFMKHLHYRIIDVSTVKELCRRWYPEEYEFAPSHRALDDISES
IKELQFYRNNIFKKK
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain6j7y Chain B Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6j7y Structural insights into nanoRNA degradation by human Rexo2.
Resolution2.203 Å
Binding residue
(original residue number in PDB)		D47 E49 D199
Binding residue
(residue number reindexed from 1)		D8 E10 D146
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.15.-
Gene Ontology
Molecular Function
GO:0000175 3'-5'-RNA exonuclease activity
GO:0003676 nucleic acid binding

View graph for
Molecular Function
External links
PDB RCSB:6j7y, PDBe:6j7y, PDBj:6j7y
PDBsum6j7y
PubMed30926754
UniProtQ9Y3B8|ORN_HUMAN Oligoribonuclease, mitochondrial (Gene Name=REXO2)

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