Structure of PDB 6j5i Chain B Binding Site BS02

Receptor Information
>6j5i Chain B (length=481) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SVDLEETGRVLSIGDGIARVHGLRNVQAEEMVEFSSGLKGMSLNLEPDNV
GVVVFGNDKLIKEGDIVKRTGAIVDVPVGEELLGRVVDALGNAIDGKGPI
GSKTRRRVGLKAPGIIPRISVREPMQTGIKAVDSLVPIGRGQRELIIGDR
QTGKTSIAIDTIINQKRFNDGTDEKKKLYCIYVAIGQKRSTVAQLVKRLT
DADAMKYTIVVSATASDAAPLQYLAPYSGCSMGEYFRDNGKHALIIYDDL
SKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDAFGGGSL
TALPVIETQAGDVSAYIPTNVISITDGQIFLETELFYKGIRPAINVGLSV
SRVGSAAQTRAMKQVAGTMKLELAQYREVALDAATQQLLSRGVRLTELLK
QGQYAPMAIEEQVAVIYAGVRGYLDKLEPSKITKFENAFLSHVISQHQAL
LGKIRADGKISEETDAKLKEIVTNFLAGFEA
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain6j5i Chain B Residue 602 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6j5i Cryo-EM structure of the mammalian ATP synthase tetramer bound with inhibitory protein IF1.
Resolution3.34 Å
Binding residue
(original residue number in PDB)		T176 D269
Binding residue
(residue number reindexed from 1)		T155 D248
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) K175 Q208 K209 R373
Catalytic site (residue number reindexed from 1) K154 Q187 K188 R352
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0032559 adenyl ribonucleotide binding
GO:0043531 ADP binding
GO:0046933 proton-transporting ATP synthase activity, rotational mechanism
Biological Process
GO:0006754 ATP biosynthetic process
GO:0015986 proton motive force-driven ATP synthesis
GO:0046034 ATP metabolic process
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005886 plasma membrane
GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)
GO:0045267 proton-transporting ATP synthase, catalytic core

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6j5i, PDBe:6j5i, PDBj:6j5i
PDBsum6j5i
PubMed31197009
UniProtP80021|ATPA_PIG ATP synthase subunit alpha, mitochondrial (Gene Name=ATP5F1A)

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