Structure of PDB 6ils Chain B Binding Site BS02

Receptor Information
>6ils Chain B (length=313) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MAPPLVVVGSANADIYVEIERLPKEGETISAKTGQTLAGGKGANQAACGA
KLMYPTYFVGRLGEDAHGKLIAEALGDDGCGVHLDYVRSVNNEPTGHAVV
MLQSDGQNSIIIVGGANMKAWPEIMSDDDLEIVRNAGIVLLQREIPDSIN
IQVAKAVKKAGVPVILDVGGMDTPIPNELLDSIDILSPNETELSRLTGMP
TETFEQISQAVAKCHKLGVKQVLVKLGSKGSALFIQGEKPIQQSIIPAAQ
VVDTTGAGDTFTAAFAVAMVEGKSHEECLRFAAAAASLCVQVKGAIPSMP
DRKSVLKLLKFSI
Ligand information
Ligand IDRIB
InChIInChI=1S/C5H10O5/c6-1-2-3(7)4(8)5(9)10-2/h2-9H,1H2/t2-,3-,4-,5+/m1/s1
InChIKeyHMFHBZSHGGEWLO-AIHAYLRMSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C1C(C(C(O1)O)O)O)O
CACTVS 3.341OC[CH]1O[CH](O)[CH](O)[CH]1O
CACTVS 3.341OC[C@H]1O[C@H](O)[C@H](O)[C@@H]1O
OpenEye OEToolkits 1.5.0C([C@@H]1[C@H]([C@H]([C@H](O1)O)O)O)O
ACDLabs 10.04OC1C(OC(O)C1O)CO
FormulaC5 H10 O5
Namealpha-D-ribofuranose;
alpha-D-ribose;
D-ribose;
ribose
ChEMBLCHEMBL606078
DrugBank
ZINCZINC000003860714
PDB chain6ils Chain B Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6ils Crystal structure and mutational analyses of ribokinase from Arabidopsis thaliana.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		N78 D80 G106 K107 N110 E210 D325
Binding residue
(residue number reindexed from 1)		N12 D14 G40 K41 N44 E144 D259
Annotation score5
Enzymatic activity
Enzyme Commision number 2.7.1.15: ribokinase.
Gene Ontology
Molecular Function
GO:0004747 ribokinase activity
GO:0016301 kinase activity
GO:0016773 phosphotransferase activity, alcohol group as acceptor
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006014 D-ribose metabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6ils, PDBe:6ils, PDBj:6ils
PDBsum6ils
PubMed30822455
UniProtA1A6H3|RBSK_ARATH Ribokinase (Gene Name=RBSK)

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