Structure of PDB 6htu Chain B Binding Site BS02
Receptor Information
>6htu Chain B (length=76) Species:
9606
(Homo sapiens) [
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HMNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEG
EGKSKKISKKNAAIAVLEELKKLPPL
Ligand information
>6htu Chain F (length=19) [
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gaggcaguuucugguacuc
...................
Receptor-Ligand Complex Structure
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PDB
6htu
The crystal structure of Staufen1 in complex with a physiological RNA sheds light on substrate selectivity.
Resolution
2.888 Å
Binding residue
(original residue number in PDB)
M181 E191 L194 F216 K232 S233 K234
Binding residue
(residue number reindexed from 1)
M2 E12 L15 F37 K53 S54 K55
Binding affinity
PDBbind-CN
: Kd=14nM
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:6htu
,
PDBe:6htu
,
PDBj:6htu
PDBsum
6htu
PubMed
30456389
UniProt
O95793
|STAU1_HUMAN Double-stranded RNA-binding protein Staufen homolog 1 (Gene Name=STAU1)
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