Structure of PDB 6hc6 Chain B Binding Site BS02

Receptor Information
>6hc6 Chain B (length=407) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RELPFKAKHAYSTISQLSEAIGPRIAGTAAEKKSALLIASSMRKLKLDVK
VQRFNIPDRLEGTLSSAGRDILLQAASGSAPTEEQGLTAPLYNAGLGYQK
DFTADAKGKIALISRGDLTYYEKAKNAEAAGAKAVIIYNNKESLVPMTPN
LSGNKVGIPVVGIKKEDGEALTQQKEATLKLKAFTNQTSQNIIGIKKPKN
IKHPDIVYVTAHYDSVPFSPGANDNGSGTSVMLEMARVLKSVPSDKEIRF
IAFGAEELGLLGSSHYVDHLSEKELKRSEVNFNLDMVGTSWEKASELYVN
TLDGQSNYVWESSRTAAEKIGFDSLSLTQGGSSDHVPFHEAGIDSANFIW
GDPETEEVEPWYHTPEDSIEHISKERLQQAGDLVTAAVYEAVKKEKAKAS
DIFEDIK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6hc6 Chain B Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6hc6 To be published
Resolution1.77 Å
Binding residue
(original residue number in PDB)		D262 E295 H401 E452
Binding residue
(residue number reindexed from 1)		D224 E257 H363 E404
Annotation score4
Enzymatic activity
Enzyme Commision number 3.4.11.10: bacterial leucyl aminopeptidase.
3.4.11.6: aminopeptidase B.
Gene Ontology
Molecular Function
GO:0008235 metalloexopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:6hc6, PDBe:6hc6, PDBj:6hc6
PDBsum6hc6
PubMed
UniProtP25152|BSAP_BACSU Aminopeptidase YwaD (Gene Name=ywaD)

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